A One-Pot Fusion of Nitrogen-Containing Heterocycles

ABSTRACT Aromatic and heteroaromatic dialkylaminoaldehydes react with various active methylene compounds in the presence of Me 3 SiCl to give functionally and structurally diverse pyrrolo[1,2-A]quinolines, pyrido[1,2-A]quinolines, pyrazolo[3,4-E]indolizines, pyrazolo[4,3-C]quinolizines, benzo[G]pyrr...

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Bibliographic Details
Published in:Synthesis (Stuttgart) 2007-09, Vol.2007 (18), p.2872-2886
Main Authors: Ryabukhin, Sergey V., Plaskon, Andrey S., Volochnyuk, Dmitriy M., Shivanyuk, Alexander N., Tolmachev, Andrey A.
Format: Article
Language:English
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Summary:ABSTRACT Aromatic and heteroaromatic dialkylaminoaldehydes react with various active methylene compounds in the presence of Me 3 SiCl to give functionally and structurally diverse pyrrolo[1,2-A]quinolines, pyrido[1,2-A]quinolines, pyrazolo[3,4-E]indolizines, pyrazolo[4,3-C]quinolizines, benzo[G]pyrrolo[1,2-A]-1,8-naphthyridines, and benzo[G]pyrido[1,2-A]-1,8-naphthyridines in high yield and excellent purity.
ISSN:0039-7881
1437-210X
DOI:10.1055/s-2007-983842