A One-Pot Fusion of Nitrogen-Containing Heterocycles

ABSTRACT Aromatic and heteroaromatic dialkylaminoaldehydes react with various active methylene compounds in the presence of Me 3 SiCl to give functionally and structurally diverse pyrrolo[1,2-A]quinolines, pyrido[1,2-A]quinolines, pyrazolo[3,4-E]indolizines, pyrazolo[4,3-C]quinolizines, benzo[G]pyrr...

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Published in:Synthesis (Stuttgart) 2007-09, Vol.2007 (18), p.2872-2886
Main Authors: Ryabukhin, Sergey V., Plaskon, Andrey S., Volochnyuk, Dmitriy M., Shivanyuk, Alexander N., Tolmachev, Andrey A.
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container_end_page 2886
container_issue 18
container_start_page 2872
container_title Synthesis (Stuttgart)
container_volume 2007
creator Ryabukhin, Sergey V.
Plaskon, Andrey S.
Volochnyuk, Dmitriy M.
Shivanyuk, Alexander N.
Tolmachev, Andrey A.
description ABSTRACT Aromatic and heteroaromatic dialkylaminoaldehydes react with various active methylene compounds in the presence of Me 3 SiCl to give functionally and structurally diverse pyrrolo[1,2-A]quinolines, pyrido[1,2-A]quinolines, pyrazolo[3,4-E]indolizines, pyrazolo[4,3-C]quinolizines, benzo[G]pyrrolo[1,2-A]-1,8-naphthyridines, and benzo[G]pyrido[1,2-A]-1,8-naphthyridines in high yield and excellent purity.
doi_str_mv 10.1055/s-2007-983842
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title A One-Pot Fusion of Nitrogen-Containing Heterocycles
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