Platinum-Catalyzed Tandem Cyclization-Nazarov Cylization Reactions: An Easy Access to Complex Carbocyclic Molecules from 2-Alkenyl-(1′-hydroxyl-4-en-2-ynyl)benzenes

Abstract In the presence of PtCl 2 /CO catalyst, 2-alkenyl-(1′-hydroxyl-4-en-2-ynyl)benzenes undergo a tandem electrophilic 6-EXO-DIG cyclization-Nazarov cyclization sequence to give 1H-cyclopenta[A]naphthalenes efficiently and regioselectively.

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Bibliographic Details
Published in:Synlett 2008-03, Vol.2008 (5), p.745-750
Main Authors: Abu Sohel, Shariar Md, Lin, Sheng-Hsun, Liu, Rai-Shung
Format: Article
Language:English
Subjects:
cluster
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Description
Summary:Abstract In the presence of PtCl 2 /CO catalyst, 2-alkenyl-(1′-hydroxyl-4-en-2-ynyl)benzenes undergo a tandem electrophilic 6-EXO-DIG cyclization-Nazarov cyclization sequence to give 1H-cyclopenta[A]naphthalenes efficiently and regioselectively.
ISSN:0936-5214
1437-2096
DOI:10.1055/s-2008-1042809