Conductance of single thiolated poly(GC)-poly(GC) DNA molecules

We use ultrahigh vacuum scanning tunneling microscopy∕spectroscopy (UHV-STM∕STS) to investigate the electronic properties of single thiolated 12-base-pair poly(GC)-poly(GC) DNA molecules on a Au(111) surface at room temperature. Reproducible current-voltage curves of the DNA are obtained at variable...

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Bibliographic Details
Published in:Applied physics letters 2005-08, Vol.87 (8), p.083902-083902-3
Main Authors: Xu, M. S., Tsukamoto, S., Ishida, S., Kitamura, M., Arakawa, Y., Endres, R. G., Shimoda, M.
Format: Article
Language:English
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Summary:We use ultrahigh vacuum scanning tunneling microscopy∕spectroscopy (UHV-STM∕STS) to investigate the electronic properties of single thiolated 12-base-pair poly(GC)-poly(GC) DNA molecules on a Au(111) surface at room temperature. Reproducible current-voltage curves of the DNA are obtained at variable sample-tip separations. The normalized conductance, which can be interpreted as the density of states, shows a well-defined wide band gap. UHV-STM∕STS opens up a novel technique to probe the electronic properties of biomolecules on surfaces at the atomic level.
ISSN:0003-6951
1077-3118
DOI:10.1063/1.2032605