Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery

Large-core hollow photonic-crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15- μ m-core hollow PCF compresses 510...

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Published in:Applied physics letters 2012-03, Vol.100 (10), p.101104-101104-4
Main Authors: Lanin, Aleksandr A., Fedotov, Il'ya V., Sidorov-Biryukov, Dmitrii A., Doronina-Amitonova, Lyubov V., Ivashkina, Olga I., Zots, Marina A., Sun, Chi-Kuang, Ömer Ilday, F., Fedotov, Andrei B., Anokhin, Konstantin V., Zheltikov, Aleksei M.
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cited_by cdi_FETCH-LOGICAL-c318t-6c769c0ba1d018352020f4aad91688d2f1032870d68e716438d8e8f395d62d783
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container_end_page 101104-4
container_issue 10
container_start_page 101104
container_title Applied physics letters
container_volume 100
creator Lanin, Aleksandr A.
Fedotov, Il'ya V.
Sidorov-Biryukov, Dmitrii A.
Doronina-Amitonova, Lyubov V.
Ivashkina, Olga I.
Zots, Marina A.
Sun, Chi-Kuang
Ömer Ilday, F.
Fedotov, Andrei B.
Anokhin, Konstantin V.
Zheltikov, Aleksei M.
description Large-core hollow photonic-crystal fibers (PCFs) are shown to enable a fiber-format air-guided delivery of ultrashort infrared laser pulses for neurosurgery and nonlinear-optical imaging. With an appropriate dispersion precompensation, an anomalously dispersive 15- μ m-core hollow PCF compresses 510-fs, 1070-nm light pulses to a pulse width of about 110 fs, providing a peak power in excess of 5MW. The compressed PCF output is employed to induce a local photodisruption of corpus callosum tissues in mouse brain and is used to generate the third harmonic in brain tissues, which is captured by the PCF and delivered to a detector through the PCF cladding.
doi_str_mv 10.1063/1.3681777
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title Air-guided photonic-crystal-fiber pulse-compression delivery of multimegawatt femtosecond laser output for nonlinear-optical imaging and neurosurgery
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