“Do-it-in-classroom” fabrication of microfluidic systems by replica moulding of pasta structures

Here, we describe a novel method for fabrication of microfluidic structures in classroom environments. This method is based on replica moulding of pasta structures in polydimethylsiloxane. Placing pasta structures on a petroleum jelly base layer enables templating round-shaped structures with contro...

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Bibliographic Details
Published in:Biomicrofluidics 2018-07, Vol.12 (4), p.044115-044115
Main Authors: Nguyen, Ngan, Thurgood, Peter, Zhu, Jiu Yang, Pirogova, Elena, Baratchi, Sara, Khoshmanesh, Khashayar
Format: Article
Language:English
Subjects:
Classrooms
Deformation
Migration
Molding (process)
Pasta
Polydimethylsiloxane
Regular
Shear stress
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Summary:Here, we describe a novel method for fabrication of microfluidic structures in classroom environments. This method is based on replica moulding of pasta structures in polydimethylsiloxane. Placing pasta structures on a petroleum jelly base layer enables templating round-shaped structures with controllable cross-sectional profiles. The pasta structures can be easily deformed and combined to create more complex 3D microfluidic structures. Proof-of-concept experiments indicate the capability of this method for studying the mixing of neighbouring flows, generation of droplets, lateral migration of particles, as well as culturing, shear stress stimulation, and imaging of cells. Our “do-it-in-classroom” method bridges the gap between the classroom and the laboratory.
ISSN:1932-1058
1932-1058
DOI:10.1063/1.5042684