First proof-of-principle of inorganic perovskites clinical radiotherapy dosimeters

Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/...

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Bibliographic Details
Published in:APL materials 2019-05, Vol.7 (5), p.051101-051101-6
Main Authors: Bruzzi, Mara, Talamonti, Cinzia, Calisi, Nicola, Caporali, Stefano, Vinattieri, Anna
Format: Article
Language:English
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Summary:Inorganic CsPbBr3 perovskite devices have been manufactured and tested as dosimeters under both conventional and Intensity Modulated Radiotherapy (IMRT) X-ray beams. Samples showed a very good linear dependence of the collected charge/current on dose/dose rates in the range of 0.1–5.0 Gy/0.1–4.0 Gy/min of interest for clinical applications. A device sensitivity of about 70 nC/Gy mm3 compares favorably with other solid-state dosimeters. The first verification of an IMRT dose profile of a prostate cancer treatment, performed by moving the perovskite device on a 10 cm-long profile with a 0.5 mm pitch, showed agreement within 5% with the dose distribution required by the treatment planning system.
ISSN:2166-532X
2166-532X
DOI:10.1063/1.5083810