Complex 3D bioprinting methods

3D bioprinting technology is evolving in complexity to enable human-scale, high-resolution, and multi-cellular constructs to better mimic the native tissue microenvironment. The ultimate goal is to achieve necessary complexity in the bioprinting process to biomanufacture fully-functional tissues and...

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Bibliographic Details
Published in:APL Bioengineering 2021-03, Vol.5 (1), p.011508-011508
Main Authors: Ji, Shen, Guvendiren, Murat
Format: Article
Language:English
Subjects:
Reviews
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Summary:3D bioprinting technology is evolving in complexity to enable human-scale, high-resolution, and multi-cellular constructs to better mimic the native tissue microenvironment. The ultimate goal is to achieve necessary complexity in the bioprinting process to biomanufacture fully-functional tissues and organs to address organ shortage and lack of patient-specific disease models. In this Review, we presented an in-depth overview of complex 3D bioprinting approaches including evolution of complex bioprinting, from simple gel-casting approach to multi-material bioprinting to omnidirectional bioprinting approaches, and emerging bioprinting approaches, including 4D bioprinting and in situ bioprinting technologies.
ISSN:2473-2877
2473-2877
DOI:10.1063/5.0034901