A bionic microdroplet array chip for particle trapping

High-efficiency particle trapping in microdroplet array has wide applications in fields such as biomedical and chemical engineering. Using a closed microdroplet array chip, consisting of a top hydrophobic surface and a bottom bioinspired hydrophilic micropore array with rounded sidewalls, the drople...

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Bibliographic Details
Published in:Physics of fluids (1994) 2025-01, Vol.37 (1)
Main Authors: Du, Lin, Ma, Lili, Zhou, Zijian, Huang, Long, Luo, Bokai, Zhou, Jia, Jing, Dalei
Format: Article
Language:English
Subjects:
Arrays
Biomedical engineering
Bionics
Chemical engineering
Contact angle
Droplets
Efficiency
Interface stability
Liquid surfaces
Trapping
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Summary:High-efficiency particle trapping in microdroplet array has wide applications in fields such as biomedical and chemical engineering. Using a closed microdroplet array chip, consisting of a top hydrophobic surface and a bottom bioinspired hydrophilic micropore array with rounded sidewalls, the droplet generation mechanism within the bionic chip is numerically and experimentally studied. During the contact between the liquid surface and the micropore, the rounded sidewalls facilitate the rupture of the liquid interface, enhancing the stability of the droplet array generated within the micropore array. By analyzing the quasi-static process when liquid enters the micropores, a void-free perfusion model is established to analyze the effects of parameters of the micropore, such as micropore size and contact angle, on the perfusion efficiency of liquid within the micropore. The particle trapping experiments confirm that particles can be effectively captured within the microdroplet array. The present work is expected to provide useful insights for enhancing the stability of the microdroplet array for high-efficiency particle trapping.
ISSN:1070-6631
1089-7666
DOI:10.1063/5.0242087