General regioselective synthesis of 2,2-disubstituted 3-hydroxyimidazolidin-4-ones

The reactions of glycine hydroxamic acid with aliphatic ketones and acetophenone are commonly used for the regioselective synthesis of cyclic hydroxamic acids 6a–e; spiro hydroxamic acid 6a was structurally characterised by X-ray diffraction analysis.

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Bibliographic Details
Published in:Mendeleev communications 2002, Vol.12 (5), p.193-196
Main Authors: Vystorop, Igor V., Lyssenko, Konstantin A., Voznesensky, Vladimir N., Lodygina, Vera P., Kostyanovsky, Remir G.
Format: Article
Language:English
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Summary:The reactions of glycine hydroxamic acid with aliphatic ketones and acetophenone are commonly used for the regioselective synthesis of cyclic hydroxamic acids 6a–e; spiro hydroxamic acid 6a was structurally characterised by X-ray diffraction analysis.
ISSN:0959-9436
DOI:10.1070/MC2002v012n05ABEH001657