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Synthesis of 1S,5R- and 1R,5S-glycoluriles by diastereospecific α-ureidoalkylation of (S)/(R)-N-carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one

A diastereospecific method for the synthesis of individual enantiomers of 1 S ,5 R - and 1 R ,5 S -glycoluriles has been developed based on the α-ureidoalkylation of ( S )/( R )- N -carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one.

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Published in:Mendeleev communications 2004, Vol.14 (6), p.253-255
Main Authors: Chikunov, Il'ya E, Kravchenko, Angelina N, Belyakov, Pavel A, Lyssenko, Konstantin A, Baranov, Vladimir V, Lebedev, Oleg V, Makhova, Nina N
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cited_by cdi_FETCH-LOGICAL-c277t-46313266be689678bb296871aefab53e7af402ac46075c01e6aa19bc933372bd3
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container_title Mendeleev communications
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creator Chikunov, Il'ya E
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description A diastereospecific method for the synthesis of individual enantiomers of 1 S ,5 R - and 1 R ,5 S -glycoluriles has been developed based on the α-ureidoalkylation of ( S )/( R )- N -carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one.
doi_str_mv 10.1070/MC2004v014n06ABEH002050
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title Synthesis of 1S,5R- and 1R,5S-glycoluriles by diastereospecific α-ureidoalkylation of (S)/(R)-N-carbamoyl-α-amino acids with 4,5-dihydroxyimidazolidin-2-one
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