Right ventricular regional deformation analysis in patients operated for tetralogy of Fallot

• Published in: Acta Cardiologica 2021-05, Vol.76 (3), p.280-287
• Main Authors: Guven, Baris, Mese, Timur, Yilmazer, Murat Muhtar, Ozdemir, Rahmi, Demirpence, Savas, Doksoz, Onder
• Format: Article
• Language: English
• Subjects: Adolescent; cardiac magnetic resonance imaging; Child; congenital heart disease; Echocardiography; Heart Ventricles - diagnostic imaging; Humans; right ventricle; strain; Stroke Volume; tetralogy of Fallot; Tetralogy of Fallot - diagnostic imaging; Tetralogy of Fallot - surgery; Ventricular Dysfunction, Right; Ventricular Function, Right
• ISSN: 0001-5385; 1784-973X; 0373-7934
• DOI: 10.1080/00015385.2020.1723880

We aimed to compare the findings of a segmental speckle-tracking strain of right ventricle with those of cardiac magnetic resonance imaging in this setting. In 26 patients with operated tetralogy of Fallot (mean age, 15.35 ± 2.3 years; range 11-18 years), right ventricular segmental speckle-straining (the basal, mid, apical segments of right ventricular septum and lateral free wall, and right ventricular apex) were determined using two-dimensional echocardiography. The echocardiographic findings were compared to right ventricular ejection fraction, right ventricular indexed end-diastolic volume, indexed end-systolic volume and pulmonary regurgitation fraction at cardiac magnetic resonance. Right ventricular global speckle strain was −18.6 ± 3.7and lateral free wall strain was −17.8 ± 4.9. Indexed right ventricular end diastolic volume was 171.7 ± 23.3 ml/m 2 , indexed right ventricular end systolic volume was 95.1 ± 35.0 ml/m 2 and right ventricular ejection fraction was 44.76 ± 9.39%. Basal inferior septum is correlated with indexed right ventricular end-diastolic volume (RVEDV; r = −0.521, p = 0.015) and pulmonary regurgitation fraction (r = −0.584, p = 0.015). Cardiac magnetic resonance (CMR)-derived RVEDV is correlated with lateral free wall (r = −0.465, p = 0.034) and Global RV (r = 0.442, p = 0.045). Right ventricular basal inferior septal and apical longitudinal strain correlates with the measures of right ventricular performance on CMR. These parameters would be useful to monitor right ventricular performance in patients after tetralogy of Fallot repair.