High sensitivity troponin and COVID-19 outcomes

Recent reports have demonstrated high troponin levels in patients affected with COVID-19. In the present study, we aimed to determine the association between admission and peak troponin levels and COVID-19 outcomes. This was an observational multi-ethnic multi-centre study in a UK cohort of 434 pati...

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Published in:Acta Cardiologica 2022-01, Vol.77 (1), p.81-88
Main Authors: Papageorgiou, Nikolaos, Sohrabi, Catrin, Prieto Merino, David, Tyrlis, Angelos, Atieh, Abed Elfattah, Saberwal, Bunny, Lim, Wei-Yao, Creta, Antonio, Khanji, Mohammed, Rusinova, Reni, Chooneea, Bashistraj, Khiani, Raj, Wijesuriya, Nadeev, Chow, Anna, Butt, Haroun, Browne, Stefan, Joshi, Nikhil, Kay, Jamie, Ahsan, Syed, Providencia, Rui
Format: Article
Language:English
Subjects:
cardiovascular disease
COVID-19
COVID-19 - complications
COVID-19 - metabolism
COVID-19 - pathology
Hospitalization
Humans
Original Scientific Paper
outcomes
Respiration, Artificial
SARS-CoV-2
Troponin
Troponin - blood
Troponin - metabolism
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Summary:Recent reports have demonstrated high troponin levels in patients affected with COVID-19. In the present study, we aimed to determine the association between admission and peak troponin levels and COVID-19 outcomes. This was an observational multi-ethnic multi-centre study in a UK cohort of 434 patients admitted and diagnosed COVID-19 positive, across six hospitals in London, UK during the second half of March 2020. Myocardial injury, defined as positive troponin during admission was observed in 288 (66.4%) patients. Age (OR: 1.68 [1.49-1.88], p 
ISSN:0001-5385
1784-973X
0373-7934
DOI:10.1080/00015385.2021.1887586