Current Trends in the Diagnosis of Vascular Prosthesis Infection

Early diagnosis of an infected vascular prosthesis, a potentially life-threatening disease, is a precondition of adequate treatment. The most frequently used diagnostic imaging method is computer tomography. Non-acute infections caused by low grade agents may pose a challenge with ambiguous CT-image...

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Bibliographic Details
Published in:Acta chirurgica belgica 2012-11, Vol.112 (6), p.405-413
Main Authors: Spacek, M., Jindrak, V., Spunda, R., Stadler, P., Lindner, J., Mitas', P., Belohlavek, O.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Blood Vessel Prosthesis - adverse effects
Citrates
Gallium
Gallium Radioisotopes
General aspects
Humans
Magnetic Resonance Imaging
Medical sciences
Multimodal Imaging
Positron-Emission Tomography
Prosthesis-Related Infections - diagnosis
Prosthesis-Related Infections - diagnostic imaging
Prosthesis-Related Infections - microbiology
Tomography, X-Ray Computed
Ultrasonography
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Summary:Early diagnosis of an infected vascular prosthesis, a potentially life-threatening disease, is a precondition of adequate treatment. The most frequently used diagnostic imaging method is computer tomography. Non-acute infections caused by low grade agents may pose a challenge with ambiguous CT-images and other ancillary imaging methods are used for these cases, each offering different levels of diagnostic sensitivity. These methods come from the fields of radiology (magnetic resonance imaging - MRI) and nuclear medicine studies using labelled leukocytes ("'In or 99m Tc- HMPAO), 99m Tc labelled antigranulocyte antibodies, 67 Ga-citrate or labelled antibiotics ( 99m Tc-ciprofloxacin) or avidin in combination with '"In-biotin. Positron emission tomography (PET) or hybrid PET/CT using 18 F-FDG are becoming increasingly popular. The authors of this review article point out the diagnostic potential of the different methods and current trends, including the possibilities of microbiological demonstration of the agent, as well as their potential position in the diagnostic algorithm.
ISSN:0001-5458
DOI:10.1080/00015458.2012.11680863