Characterization of Phenolics in Lavandula angustifolia

The lavender flowers and their essential oil are widely used in therapy in Romania and the European Community. Since the European Pharmacopoeia only allows the use of Lavandula sp flowers for medicinal purposes, the objective of this study was to investigate the chemical composition of Lavandula ang...

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Bibliographic Details
Published in:Analytical letters 2017-11, Vol.50 (17), p.2839-2850
Main Authors: Radulescu, Cristiana, Stihi, Claudia, Ilie, Mihaela, Lazurcă, Dumitru, Gruia, Romulus, Olaru, Octavian Tudorel, Bute, Oana Catalina, Dulama, Ioana Daniela, Stirbescu, Raluca Maria, Teodorescu, Sofia, Florescu, Monica
Format: Article
Language:English
Subjects:
Chlorogenic acid
Chromatography
Extraction
Flowers
Gallic acid
high-performance thin-layer chromatography
Infrared analysis
Infrared spectroscopy
infrared spectroscopy with attenuated total reflectance
Lavandula sp
Pharmacology
polyphenols
Propylene
Raman spectroscopy
Reflectance
Spectrum analysis
Thin layer chromatography
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Summary:The lavender flowers and their essential oil are widely used in therapy in Romania and the European Community. Since the European Pharmacopoeia only allows the use of Lavandula sp flowers for medicinal purposes, the objective of this study was to investigate the chemical composition of Lavandula angustifolia extracts obtained by ultrasound-assisted extraction, rapid pressurized extraction at 6.7 bar, and subcritical fluid extraction. The solvents used for the first two methods were mixtures of water and alcohol, glycerin, and propylene glycol. These extracts were analyzed by high-performance thin-layer chromatography, infrared spectroscopy with attenuated total reflectance, and Raman spectroscopy. The total phenolics were evaluated using a modified Folin-Ciocalteu method. The primary phenolics were chlorogenic acid, gallic acid, umbelliferone, luteolin 7-O-glucoside, vitexin, and isoquercitroside. The extracts were variable in composition, with the highest yield by subcritical fluid extraction, followed by extraction at 6.7 bar. The infrared and Raman spectroscopy results confirmed the chromatography measurements.
ISSN:0003-2719
1532-236X
DOI:10.1080/00032719.2016.1264409