High-Sensitivity and High-Performance Determination of Trace Aluminum in Water for Pharmaceutical Purposes by Microwave Plasma and Inductively Coupled Plasma-Atomic Emission Spectrometry

Procedures for the determination of aluminum in water for injections (Aqua ad iniectabilia) and high-purity water (Aqua valde purificata) at a level of several µg L −1 using atomic-emission spectrometry with a novel microwave plasma (MP-AES) and inductively coupled plasma (ICP-AES) are proposed. Reg...

Full description

Saved in:
Bibliographic Details
Published in:Analytical letters 2018-03, Vol.51 (5), p.659-672
Main Authors: Samarina, T. O., Volkov, D. S., Mikheev, I. V., Proskurnin, M. A.
Format: Article
Language:English
Subjects:
Acidification
Aluminum
Atomic emission spectroscopy
Cost analysis
Emission analysis
high-purity water
ICP-AES
Inductively coupled plasma
microwave-introduced plasma
MP-AES
Pharmacology
Plasma
Scientific imaging
Sensitivity
Spectrometry
Water purification
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Procedures for the determination of aluminum in water for injections (Aqua ad iniectabilia) and high-purity water (Aqua valde purificata) at a level of several µg L −1 using atomic-emission spectrometry with a novel microwave plasma (MP-AES) and inductively coupled plasma (ICP-AES) are proposed. Regardless of the atomic-emission technique used, the procedure for aluminum needs no sample preparation (acidification only), no preconcentration, shows high sensitivity (limits of detection of 0.4 and 0.7 µg L −1 for ICP-AES and MP-AES with a polymeric inert concentric nebulizer, respectively, and 0.03 µg L −1 for ICP-AES with an ultrasonic nebulizer), high precision (repeatability, relative standard deviation,
ISSN:0003-2719
1532-236X
DOI:10.1080/00032719.2017.1348510