Terahertz imaging technique for cancer diagnostics using frequency conversion by gold nano-objects

A technique is suggested (that includes the device's scheme and assessments of its feasibility) for imaging cancer cells in biological tissue samples in vitro and in human skin in vivo, exposing them to 4.2 THz radiation and using a THz-to-infrared (IR) converter in combination with an IR sensi...

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Bibliographic Details
Published in:Ferroelectrics 2017-03, Vol.509 (1), p.158-166
Main Authors: Moldosanov, K. A., Postnikov, A. V., Lelevkin, V. M., Kairyev, N. J.
Format: Article
Language:English
Subjects:
Cancer
Condensed Matter
embedded nanoparticles
Embedding
Gold
heat dissipation by nanoparticles
Heat exchange
Imaging techniques
In vivo methods and tests
Infrared cameras
infrared detection
Materials Science
Medical imaging
Nanoparticles
Physics
Polytetrafluoroethylene
terahertz absorption
Terahertz-to-infrared converter
Tissues
tumor imaging
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Description
Summary:A technique is suggested (that includes the device's scheme and assessments of its feasibility) for imaging cancer cells in biological tissue samples in vitro and in human skin in vivo, exposing them to 4.2 THz radiation and using a THz-to-infrared (IR) converter in combination with an IR sensitive camera. The converter includes a system of gold nanoparticles embedded into a substance transparent in THz and IR, e.g., Teflon®. The heat exchange between gold nanoparticles and their embedding substance is simulated in a calculation. The convenient size of nanoparticles and their concentration in the substrate are estimated.
ISSN:0015-0193
1563-5112
DOI:10.1080/00150193.2017.1296344