Predicting variceal bleeding in patients with biliary atresia

Background/aims: Variceal bleeding is the main cause of morbidity and mortality in children with portal hypertension and biliary atresia. The aim of this study is to predict high-risk varices by analyzing various clinical factors, thus improve prognosis of patients with biliary atresia. Methods: A t...

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Bibliographic Details
Published in:Scandinavian journal of gastroenterology 2019-11, Vol.54 (11), p.1385-1390
Main Authors: Sohn, Hanbyul, Park, Sowon, Kang, Yunkoo, Koh, Hong, Han, Seok Joo, Kim, Seung
Format: Article
Language:English
Subjects:
Children
endoscopy
Kasai portoenterostomy
transient elastrography
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Summary:Background/aims: Variceal bleeding is the main cause of morbidity and mortality in children with portal hypertension and biliary atresia. The aim of this study is to predict high-risk varices by analyzing various clinical factors, thus improve prognosis of patients with biliary atresia. Methods: A total of 157 patients with biliary atresia who underwent Kasai portoentrostomy were enrolled in a single center. Clinical data including laboratory values, endoscopic findings and values of transient elastography (FibroScan ® ) were analyzed retrospectively. Results: The bleeding group and the non-bleeding group showed statistically significant differences in several variables; The FibroScan ® value (HR 1.05, 95% CI (1.03-1.07), p  
ISSN:0036-5521
1502-7708
DOI:10.1080/00365521.2019.1683225