β-Chlorocinnamonitriles in a New Synthesis of 3-Functionally Substituted 6-amino-1,2-Dihydropyridin-2-ones

β-Chlorocinnamonitriles react with methylene-active compounds containing N-substituted carboxamide group in DMSO solution in the presence of potassium hydroxide, forming 3-functionally substituted 1,2-dihydropyridin-2-ones.

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Bibliographic Details
Published in:Synthetic communications 2008-05, Vol.38 (12), p.1984-1989
Main Authors: Trofymchuk, Sergii A., Tolmachov, Andrij O., Kondratyuk, Kostàntyn M., Volovenko, Yulian M., Lebed, Pavlo S., Vovk, Mykhaylo V.
Format: Article
Language:English
Subjects:
3-functionally substituted 1,2-dihydropyridin-2-ones
Anilides of malonic and acetoacetic acids
N-monosubstituted cyanoacetamides
β-chlorocinnamonitriles
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Description
Summary:β-Chlorocinnamonitriles react with methylene-active compounds containing N-substituted carboxamide group in DMSO solution in the presence of potassium hydroxide, forming 3-functionally substituted 1,2-dihydropyridin-2-ones.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397910801997777