Novel Method of Reducing Ketones Using Sodium Hydroxide in Isopropanol

Ketones are readily reduced to secondary alcohols with sodium hydroxide in refluxing isopropanol.

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Bibliographic Details
Published in:Synthetic communications 2010-03, Vol.40 (8), p.1187-1191
Main Authors: Zuidema, Daniel R., Wert, Katherine J., Williams, Sarah L., Chill, Samuel T., Holte, Kimberly L., Kokes, Nathanael K., Mebane, Robert C.
Format: Article
Language:English
Subjects:
Hydrogen transfer
ketone reduction
preparation of secondary alcohols
sodium hydroxide
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Description
Summary:Ketones are readily reduced to secondary alcohols with sodium hydroxide in refluxing isopropanol.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397910903061043