Novel Synthesis of Isoquinoline Derivatives Derived from (Z)-4-(1,3-Diphenylpyrazol-4-yl)isochromene-1,3-dione

A series of isoquinoline derivatives were synthesized via the reaction of the (Z)-4-(1,3-diphenylpyrazol-4-yl)isochromene-1,3-dione with different hydrazides, primary amines, diamines, 2-aminothiophenol, 2-aminobenzoic acid, p-aminoacetophenone, and ethyl 2-amino-4,5,6,7-tetrahydrobenzo-[b]thiophene...

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Bibliographic Details
Published in:Synthetic communications 2015-07, Vol.45 (14), p.1632-1641
Main Authors: Mahmoud, Mahmoud R., El-Shahawi, Manal M., Abou-Elmagd, Wael S. I., Hekal, Mohamed H.
Format: Article
Language:English
Subjects:
Fused heterocycles
isochromene-1,3-dione
isoquinoline
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Summary:A series of isoquinoline derivatives were synthesized via the reaction of the (Z)-4-(1,3-diphenylpyrazol-4-yl)isochromene-1,3-dione with different hydrazides, primary amines, diamines, 2-aminothiophenol, 2-aminobenzoic acid, p-aminoacetophenone, and ethyl 2-amino-4,5,6,7-tetrahydrobenzo-[b]thiophene-3-carboxylate. All the synthesized compounds were characterized by infrared, 1 H NMR, and mass spectra besides the analytical data.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397911.2015.1030760