EPIDIDYMAL SCANNING ELECTRON MICROSCOPY STUDY IN HYPOTHYROID RATS

The purpose of this research was to investigate, using scanning electron microscopy, the effect of hypothyroidism on the ultrastructure of the rat cauda epididymis. Thyroidectomy was obtained by ip injection of 270 µCi of 131I per rat. One month later, several portions of cauda epididymis were exami...

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Bibliographic Details
Published in:Archives of andrology 2001, Vol.46 (1), p.73-77
Main Author: A. G. Del Rio, L. A. Palaoro, A. M. Blanco, H. Niepomniszcze
Format: Article
Language:English
Subjects:
Epididymal Morphology Hypothyroidism Thyroid Gland
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Summary:The purpose of this research was to investigate, using scanning electron microscopy, the effect of hypothyroidism on the ultrastructure of the rat cauda epididymis. Thyroidectomy was obtained by ip injection of 270 µCi of 131I per rat. One month later, several portions of cauda epididymis were examined. Morphological and physiological differences were detected in the cauda epididymis of the hypothyroid animals when compared to the control normal rats. The hypothyroid condition was associated with important changes in the luminal surface of the cauda epididymis epithelium. Broken, oblique, and loss of stereocilia, denuded epithelial cells, and flattening of the tubule were observed. The results confirm that hypothyroidism causes marked structural changes in the cauda ductus epididymis and could be adversely affect sperm maturation motility.
ISSN:0955-3002
0148-5016
1362-3095
1521-0375
DOI:10.1080/01485010117410