Solid Papillary Carcinoma of the Breast: Report of Two Cases

Two cases of solid papillary carcinoma of the breast were pathologically studied. Subjects included two female patients: a 76-year-old (Case 1) and a 43-year-old (Case 2). Both cases showed solid and papillary proliferation of spindle cells in expanded ducts, perivascular pseudorosettes, eosinophili...

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Bibliographic Details
Published in:Ultrastructural pathology 2001, Vol.25 (2), p.147-152
Main Author: Chizuko Kanbayashi, Kuniyuki Oka, Hando Hakozaki, Hidetoshi Saito, Norimasa Sando, Tomomi Tobita, Sumiko Koyamatsu, Takuya Moriya, Naoyoshi Mori
Format: Article
Language:English
Subjects:
Adult
Aged
Alcian Blue
Biopsy
Breast Mucinous Granule Neuroendocrine Granule Solid Papillary Carcinoma
Breast Neoplasms - ultrastructure
Carcinoma, Papillary - ultrastructure
Cytoplasm - ultrastructure
Cytoplasmic Granules - ultrastructure
Diagnosis, Differential
Female
Histocytochemistry
Humans
Immunohistochemistry
Microscopy, Electron
Mitosis
Mucins - biosynthesis
Periodic Acid-Schiff Reaction
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Summary:Two cases of solid papillary carcinoma of the breast were pathologically studied. Subjects included two female patients: a 76-year-old (Case 1) and a 43-year-old (Case 2). Both cases showed solid and papillary proliferation of spindle cells in expanded ducts, perivascular pseudorosettes, eosinophilic fine granules in an abundant cytoplasm, intracellular mucin production, and positivity for chromogranin A. Case 1 showed an aggregation form involving multiple ducts, admixture of signet-ring like cells, mucin pools, and small and large electron-dense granules and flocculent granules in electron microscopy. Case 2 showed a solitary and compact form in a dilated duct and an interlacing bundle pattern.
ISSN:0191-3123
1521-0758
DOI:10.1080/01913120117865