The relationship between heart rate and VO 2 in moderate-to-severe asthmatics

• Published in: The Journal of asthma 2020-07, Vol.57 (7), p.713-721
• Main Authors: Rodrigues Mendes, Felipe A, Teixeira, Renata Nakata, Martins, Milton A, Cukier, Alberto, Stelmach, Rafael, Medeiros, Wladimir Musetti, Carvalho, Celso R F
• Format: Article
• Language: English
• Subjects: Adult; Asthma - diagnosis; Asthma - physiopathology; Cross-Sectional Studies; Exercise Test; Female; Heart Rate - physiology; Humans; Male; Middle Aged; Pulmonary Gas Exchange - physiology; Severity of Illness Index; Young Adult
• ISSN: 0277-0903; 1532-4303
• DOI: 10.1080/02770903.2019.1606235

The main purpose of this study was to evaluate whether the %HRR-%VO R relationship and %HRR-VO relationship are affected in patients with moderate or severe asthma and whether airway obstruction and aerobic capacity influence these relationships. A linear regression was calculated using the paired %VO R-%HRR and %VO -%HRR for 93 subjects with asthma. The mean slope and -intercept were calculated and compared with the line of identity ( -intercept = 0, slope = 1) for all patients and subgroups for the following conditions: low and normal VO and low and normal FEV . The slope and intercepts of %VO R-%HRR were similar to the line of identity for all groups (  > 0.05), and the regressions between %HRR and %VO did not coincide with the line of identity for all groups (   0.05) or FEV (  > 0.05). This is the first study to confirm a constant equivalence between %HRR and %VO R in outpatients with moderate or severe asthma. Our data also suggest that the relationship between %HRR and %VO is unreliable. These results support the use of %HRR in relation to %VO R to estimate exercise intensity in this population, independently of the pulmonary function and fitness level.