Effects of cadmium and chlordane on cellular apoptosis in ecotoxicological test species

Cadmium and chlordane are compounds chosen for a preliminary study on the impact of environmental contaminants on apoptosis in different representative species. These two potentially toxic substances decrease in vitro apoptosis of Daphnia magna cells. This appears to be related to the chemical conce...

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Bibliographic Details
Published in:Toxicological and environmental chemistry 2001-06, Vol.81 (3-4), p.153-160
Main Authors: Zeroual, F. Z., Guerbet, M., Nguyen-Ba, G., Jouany, J. M.
Format: Article
Language:English
Subjects:
Apoptosis
Cadmium
Chlordane
Daphnia magna
SHE
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Summary:Cadmium and chlordane are compounds chosen for a preliminary study on the impact of environmental contaminants on apoptosis in different representative species. These two potentially toxic substances decrease in vitro apoptosis of Daphnia magna cells. This appears to be related to the chemical concentrations and the time exposure. Cadmium was also directly introduced to the cell culture medium of Syrian hamster embryos (SHE) or indirectly via daphnids, which had firstly consumed algae contaminated with cadmium. A very sharp transfer of cadmium toxicity from algae to daphnids is noted and an inhibition of the apoptosis in SHE cells can be observed.
ISSN:0277-2248
1029-0486
DOI:10.1080/02772240109359028