Voltammetric determination of a fluoroquinolone antibiotic based on multilayer reduced graphene oxide sensor prepared directly, promptly by electrochemically expanding graphite electrode surface

Ciprofloxacin (Cip), a fluoroquinolone antibiotic, was determined by linear sweep adsorptive stripping voltammetric method using multilayer reduced graphene oxide electrode (m-rGO). The m-rGO electrode was fabricated directly, simply and promptly from graphite platform by potentiostatic technique wi...

Full description

Saved in:
Bibliographic Details
Published in:International journal of environmental analytical chemistry 2023-12, Vol.ahead-of-print (ahead-of-print), p.1-17
Main Authors: Do, Ba Vuong, Nguyen, Hoang Anh, Nguyen, Thi Lieu, Vu, Thi Thu Ha, Le, Quoc Hung, Pham, Hong Phong, Ta, Thi Thao, Pham, Thi Hai Yen
Format: Article
Language:English
Subjects:
Adsorptivity
Analytical methods
Antibiotics
Catalysis
Catalysts
Ciprofloxacin
electrochemical sensor
Electrochemistry
Electrodes
Fabrication
fluoroquinolone antibiotic
Functional groups
Graphene
Graphite
graphite expansion
Lakes
multilayer reduced graphene oxide
Multilayers
Voltammetry
Water analysis
Water sampling
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Ciprofloxacin (Cip), a fluoroquinolone antibiotic, was determined by linear sweep adsorptive stripping voltammetric method using multilayer reduced graphene oxide electrode (m-rGO). The m-rGO electrode was fabricated directly, simply and promptly from graphite platform by potentiostatic technique without further modification. The produced electrode exhibited excellent performance for ciprofloxacin (Cip) determination with a much higher signal of Cip than that on the initial graphite electrode (13.4 times). This dominance of the m-rGO electrode resulted from the large electrochemically active surface area, electrochemical catalysis, suitable functional groups on the electrode surface. Experimental conditions such as the electrode fabrication time, the supporting solution, and accumulation time were optimised to obtain the Cip highest signal. A Cip analytical method established under the optimal conditions had a good linear relationship between the Cip signal with its concentration range from 0.5 to 20 µM (R 2  = 0.9953). The method showed a low detection limit (LOD = 0.078 µM), satisfactory reproducibility (RSD = 1.50%), and high accuracy. Cip concentration in a spiked lake water sample determined by the proposed method with acceptable precision (RSD = 5.59%) and trueness (recovery = 94.2-106.3%) was comparable with LC-MS/MS method.
ISSN:0306-7319
1029-0397
DOI:10.1080/03067319.2021.1982924