Contamination of Marek's disease vaccine suspensions with Enterococcus faecalis and its possible role in amyloid arthropathy

Samples of hatchery air (hatcher and processing room), Marek's disease vaccine suspensions and injection needles collected during chick processing, revealed variable levels (< 500 to 10 6 colony forming units (cfu)/m 3 air, < 10 to 10 6 cfu/ml vaccine suspension, and 9500 to 61000 cfu/nee...

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Bibliographic Details
Published in:Avian pathology 2000-02, Vol.29 (1), p.21-25
Main Authors: Landman, W.J.M, Veldman, K.T, Mevius, D.J, Doornenbal, P
Format: Article
Language:English
Subjects:
AMYLOID
AVES DE CORRAL
Bacteria
CONTAMINACION
CONTAMINATION
Disease
ECLOSERIE
ENFERMEDAD DE MAREK
ENFERMEDADES DE LAS ARTICULACIONES
FOWLS
HATCHERIES
JOINT DISEASES
LOCAL PARA INCUBACION
MALADIE DE MAREK
MALADIE DES ARTICULATIONS
MAREK'S DISEASE
MAREK'S DISEASE VIRUS
NETHERLANDS
PAISES BAJOS
Pathology
PAYS BAS
POULTRY
STREPTOCOCCUS FAECALIS
VACCIN
VACCINATION
VACCINES
VACUNA
VACUNACION
VIRUS ENFERMEDAD DE MAREK
VIRUS MALADIE DE MAREK
VOLAILLE
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Summary:Samples of hatchery air (hatcher and processing room), Marek's disease vaccine suspensions and injection needles collected during chick processing, revealed variable levels (< 500 to 10 6 colony forming units (cfu)/m 3 air, < 10 to 10 6 cfu/ml vaccine suspension, and 9500 to 61000 cfu/needle) of Enterococcus faecalis contamination. This observation suggests a possible infection route in 1-day-old chickens through intramuscular vaccination of Marek's disease vaccine contaminated with arthropathic and amyloidogenic E. faecalis, which could lead to amyloid arthropathy. Pulsed-field gel electrophoresis (PFGE) DNA restriction endonuclease fragment analysis of E. faecalis strains obtained from two hatcheries revealed a predominant PFGE pattern in one hatchery, while one isolate with an almost identical PFGE pattern to an amyloid arthropathy inducing isolate was found.
ISSN:0307-9457
1465-3338
DOI:10.1080/03079450094234