A ligand-based ELISA for detection of soluble asialoglycoprotein receptor in human serum

A ligand-based enzyme-linked immunosorbent assay (ELISA) for the soluble form of functional asialoglycaoprotein receptor (s-ASGPR) in human serum has been developed. This assay was evaluated and proved to show good stability, which is suitable for testing human serum. Clinical serum samples were col...

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Bibliographic Details
Published in:Journal of carbohydrate chemistry 2021-11, Vol.40 (7-9), p.440-453
Main Authors: Hu, Jing, Zhao, Ming, Shi, Qimin, Li, Lingxin, Yin, Jian
Format: Article
Language:English
Subjects:
Asialoglycoprotein receptor (ASGPR)
ELISA
human serum
ligand
liver function
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Summary:A ligand-based enzyme-linked immunosorbent assay (ELISA) for the soluble form of functional asialoglycaoprotein receptor (s-ASGPR) in human serum has been developed. This assay was evaluated and proved to show good stability, which is suitable for testing human serum. Clinical serum samples were collected and tested with the established assay. The contents of serum s-ASGPR in healthy group and liver injury group were compared (p 
ISSN:0732-8303
1532-2327
DOI:10.1080/07328303.2021.2008952