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Factors associated with diagnostic discrepancy for left ventricular hypertrophy between electrocardiography and echocardiography

Objective: To investigate the influence of cardiovascular risk factors, including fasting plasma glucose (FPG), on the association between electrocardiographic (ECG) and echocardiographic left ventricular hypertrophy (LVH) in an elderly population. Methods: We tested cross-sectional associations bet...

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Published in:Blood pressure 2017-01, Vol.26 (1), p.54-63
Main Authors: Petersen, Søren Sandager, Pedersen, Line Reinholdt, Pareek, Manan, Nielsen, Mette Lundgren, Diederichsen, Søren Zöga, Leósdóttir, Margrét, Nilsson, Peter M., Diederichsen, Axel Cosmus Pyndt, Olsen, Michael Hecht
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Language:English
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Summary:Objective: To investigate the influence of cardiovascular risk factors, including fasting plasma glucose (FPG), on the association between electrocardiographic (ECG) and echocardiographic left ventricular hypertrophy (LVH) in an elderly population. Methods: We tested cross-sectional associations between electrocardiographic and echocardiographic LVH, defining LVH according to the Sokolow-Lyon voltage combination, Cornell voltage-duration product, or left ventricular mass index (LVMI). Differences between standardized LVMI and Sokolow-Lyon voltage combination or Cornell voltage-duration product (absolute value/cut-off value for LVH) were used as outcome variables in order to identify explanatory variables associated with diagnostic discrepancies between ECG and echocardiography. Results: Of the 1382 subjects included, 77% did not display any signs of LVH, 6% had LVH defined by ECG only, 13% had LVH defined by echocardiography only, and 5% had LVH on both ECG and echocardiography. Older subjects and those with higher blood pressure and RWT were more likely to have a relatively greater LVMI on echocardiography than that predicted on ECG (odds ratio: 1.65 per 10 years (95% confidence interval (CI): 1.27-2.15), p = .0002, odds ratio: 1.17 per 10 mmHg (95% CI: 1.09-1.25), p 
ISSN:0803-7051
1651-1999
DOI:10.1080/08037051.2016.1235959