A Review of Cyclodestructive Procedures for the Treatment of Glaucoma

Cyclodestruction aims to reduce aqueous humor production through the coagulation or destruction of the ciliary body and has been an important treatment choice for glaucoma since the 1930s. The purpose of the current review is to highlight the evidence regarding the safety and efficacy of various cyc...

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Bibliographic Details
Published in:Seminars in ophthalmology 2020-08, Vol.35 (5-6), p.261-275
Main Authors: Anand, Nandita, Klug, Emma, Nirappel, Abraham, Solá-Del Valle, David
Format: Article
Language:English
Subjects:
Cyclodestruction
endoscopic photocoagulation
high- intensity focused ultrasound
micropulse diode
transcleral diode laser
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Summary:Cyclodestruction aims to reduce aqueous humor production through the coagulation or destruction of the ciliary body and has been an important treatment choice for glaucoma since the 1930s. The purpose of the current review is to highlight the evidence regarding the safety and efficacy of various cyclodestructive modalities, emphasizing peer-reviewed articles from the last 20 years and the most common variants of these procedures. The review focuses primarily on the two most common variants of transscleral cyclophotocoagulation (TS-CPC), continuous-wave diode cyclophotocoagulation (CW-TSCPC) and MicroPulse diode cyclophotocoagulation (MP-TSCPC) as well as endoscopic cyclophotocoagulation (ECP) and high-intensity focused ultrasound cyclodestruction (HIFU). We believe that the role of cyclodestruction in glaucoma treatment will only continue to expand given the advances in the field, particular with regards to targeted ciliary body destruction and improvement in the safety profile.
ISSN:0882-0538
1744-5205
DOI:10.1080/08820538.2020.1810711