EPISODES OF FEVER AND NEUTROPENIA IN CHILDREN WITH CANCER IN A TERTIARY CARE MEDICAL CENTER IN TURKEY

The aim of this study was to determine the clinical features and microbiological spectrum during episodes of fever and neutropenia (FEN) in children with cancer. Demographics, clinical information, treatment approaches, and outcomes of the patients admitted to Akdeniz University Department of Pediat...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric hematology and oncology 2006-04, Vol.23 (3), p.217-229
Main Authors: Tezcan, Gulsun, Kupesiz, Alphan, Ozturk, Feryal, Ogunc, Dilara, Gultekin, Meral, Yesilipek, Akif, Hazar, Volkan
Format: Article
Language:English
Subjects:
Adolescent
Anti-Bacterial Agents - therapeutic use
Antineoplastic Combined Chemotherapy Protocols - adverse effects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Bacterial Infections - complications
Bacterial Infections - epidemiology
cancer
Candidiasis - complications
Candidiasis - epidemiology
Catheterization, Central Venous - adverse effects
Child
Child, Preschool
children
Disease Progression
febrile neutropenia
Female
Fever - epidemiology
Fever - etiology
Gram-Negative Bacterial Infections - complications
Gram-Negative Bacterial Infections - drug therapy
Gram-Negative Bacterial Infections - epidemiology
Gram-Positive Bacterial Infections - complications
Gram-Positive Bacterial Infections - drug therapy
Gram-Positive Bacterial Infections - epidemiology
Humans
Hypotension - epidemiology
Infant
Male
Neoplasms - complications
Neoplasms - drug therapy
Neutropenia - chemically induced
Neutropenia - complications
Neutropenia - epidemiology
Prognosis
Retrospective Studies
Risk Factors
Treatment Outcome
Turkey - epidemiology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The aim of this study was to determine the clinical features and microbiological spectrum during episodes of fever and neutropenia (FEN) in children with cancer. Demographics, clinical information, treatment approaches, and outcomes of the patients admitted to Akdeniz University Department of Pediatric Hematology and Oncology from October 1996 to June 2004 were evaluated retrospectively. Of the total 621 episodes, 345 (55.5%) were microbiologically documented (MDI) (36.4%) or clinically suspected (CSI) (19.2%) infections. A total of 425 infections were diagnosed in 345 episodes, in which lower respiratory tract infections were the most common (32.7%). Among the microbiologically documented infections, Staphylococci (both coagulase-negative and coagulase-positive) (38.7%) and Escherichia coli (12.9%) were the most frequently isolated gram-positive and gram-negative organisms, respectively. Monocytopenia less than 100/μL (p = 0.01), duration of neutropenia (p =. 01) and fever (p
ISSN:0888-0018
1521-0669
DOI:10.1080/08880010500506719