ORAL AND DENTAL FINDINGS IN FANCONI'S ANEMIA

Fanconi's anemia is an autosomal recessive disorder characterized by progressive pancytopenia and congenital malformation of the skeleton. This study investigated the oral health status of 15 children with Fanconi's anemia, including oral lesions, gingival and periodontal status, and denta...

Full description

Saved in:
Bibliographic Details
Published in:Pediatric hematology and oncology 2005-09, Vol.22 (6), p.531-539
Main Authors: Açikgöz, Aydan, Özden, Feyza Otan, Fisgin, Tunç, Açikgöz, Gokhan, Duru, Feride, Yarali, Nese, Albayrak, Davut
Format: Article
Language:English
Subjects:
Adolescent
Adult
Alveolar Bone Loss - complications
Alveolar Bone Loss - diagnostic imaging
Child
dental abnormality
Fanconi Anemia - complications
Fanconi's anemia
Female
gingivitis
Humans
Male
Mouth Abnormalities - complications
Mouth Abnormalities - diagnostic imaging
oral lesions
periodontitis
Periodontitis - complications
Periodontitis - diagnostic imaging
Radiography
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Fanconi's anemia is an autosomal recessive disorder characterized by progressive pancytopenia and congenital malformation of the skeleton. This study investigated the oral health status of 15 children with Fanconi's anemia, including oral lesions, gingival and periodontal status, and dental abnormalities. All children in the group were found to have a tendency to develop tooth decay and were in need of dental treatment. Two had aggressive periodontitis. In one patient supernumerary teeth were found, while in another teeth were congenitally missing. The increased tendency toward periodontal disease in patients with Fanconi's anemia may be due not only to the anemia, leukopenia, and defective detoxification of oxygen radicals that are characteristic of the disease itself, but also to medications applied during intense immunosuppressive treatment, such as prednisolone.
ISSN:0888-0018
1521-0669
DOI:10.1080/08880010591002413