Plasma D -Lactate Levels in Diagnosis of Appendicitis

We investigated the possible use of D -lactate as a predictor in the diagnosis of appendicitis. C-reactive protein level (CRP) and leukocyte counts were also evaluated. Venous blood D -lactate, CRP, and leukocyte counts were measured preoperatively in 53 patients undergoing surgery for appendicitis,...

Full description

Saved in:
Bibliographic Details
Published in:Journal of investigative surgery 2003, Vol.16 (4), p.233-237
Main Authors: Cağlayan, Fatma, Cakmak, Murat, Cağlayan, Osman, Cavuşoglu, Turgut
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Appendicitis
Appendicitis - blood
Appendicitis - diagnosis
Biomarkers
C-Reactive Protein - metabolism
Child
Crp, D -lactate
Humans
Lactic Acid - blood
Leukocyte Count
Middle Aged
Predictive Value of Tests
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We investigated the possible use of D -lactate as a predictor in the diagnosis of appendicitis. C-reactive protein level (CRP) and leukocyte counts were also evaluated. Venous blood D -lactate, CRP, and leukocyte counts were measured preoperatively in 53 patients undergoing surgery for appendicitis, as well as in 20 healthy subjects. Levels of all three parameters in the surgical patients were significantly higher than in the control group ( p < .05). Previous studies have shown that venous D -lactate is more specific to the intestine than CPR or leukocyte count. Based on our data, venous D -lactate, which had the lowest false-negative rate among these laboratory parameters, may be a useful diagnostic marker for appendicitis. None of these parameters were helpful in identifying the type of the appendicitis.
ISSN:0894-1939
1521-0553
DOI:10.1080/08941930390215033