Photodynamic Therapy for Subfoveal Classic Choroidal Neovascularization Related to Punctate Inner Choroidopathy (PIC) or Presumed Ocular Histoplasmosis-Like Syndrome (POHS-Like)

Purpose: To evaluate the safety and efficacy of photodynamic therapy with verteporfin (PDT) for subfoveal classic choroidal neovascularization (CNV) related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like). Methods: Retrospective review of 16 eyes fro...

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Published in:Ocular immunology and inflammation 2005-10, Vol.13 (5), p.361-366
Main Authors: Postelmans, Laurence, Pasteels, Brigitte, Coquelet, Pascale, Caspers, Laure, Verougstraete, Claire, Leys, Anita, Wirix, Mieke, Mauget-Faÿsse, Martine, Quaranta, Maddalena, Rolland, Florence, Snyers, Bernadette, Smets, Erica
Format: Article
Language:English
Subjects:
Adolescent
Adult
Chorioretinitis
choroidal neovascularization
Choroidal Neovascularization - drug therapy
Choroidal Neovascularization - etiology
Eye Infections, Fungal - complications
Eye Infections, Fungal - drug therapy
Female
Fluorescein Angiography
Follow-Up Studies
Fovea Centralis
Fundus Oculi
Histoplasmosis - complications
Histoplasmosis - drug therapy
Humans
Male
Middle Aged
Photochemotherapy
photodynamic therapy
Photosensitizing Agents - therapeutic use
Porphyrins - therapeutic use
presumed ocular histoplasmosis syndrome
punctate inner choroidopathy
Retrospective Studies
Syndrome
Treatment Outcome
Visual Acuity
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Summary:Purpose: To evaluate the safety and efficacy of photodynamic therapy with verteporfin (PDT) for subfoveal classic choroidal neovascularization (CNV) related to punctate inner choroidopathy (PIC) or presumed ocular histoplasmosis-like syndrome (POHS-like). Methods: Retrospective review of 16 eyes from 14 patients with subfoveal classic CNV associated with PIC or POHS-like and treated with PDT. Results: The mean visual acuity increased from 4.5/10 (range: 1/10-9/10) to 7/10 (range: 2/10-10/10) after a mean follow-up of 21 months (range: 8-32 months) and a mean number of 2 PDT (range: 1-6). Visual acuity remained stable or improved in 13 of the 16 eyes (81%) and decreased in three. Conclusion: This nearly two-year follow-up study suggests that PDT could be helpful for patients with subfoveal classic CNV related to PIC or POHS-like.
ISSN:0927-3948
1744-5078
DOI:10.1080/09273940590951124