The Impact of Severe COVID-19 on Corneal Endothelial Cells-Analysis of the In Vivo Noncontact Specular Microscopy

This study aimed to investigate the effects of severe COVID-19 infection on the corneal endothelium via in vivo specular microscopy. This was an observational, prospective, and controlled study including 56 eyes of 56 severe COVID-19 patients, compared to after-recovery and 56 eyes of 56 age- and ge...

Full description

Saved in:
Bibliographic Details
Published in:Ocular immunology and inflammation 2024-09, Vol.ahead-of-print (ahead-of-print), p.1-9
Main Authors: Bayram, Nurettin, Ozsaygılı, Cemal, Gundogan, Medine, Unal, Sefa, Bagci, Fatma, Pangal, Emine, Yuvacı, İ̇sa
Format: Article
Language:English
Subjects:
Adult
Aged
Cell Count
Cornea
Corneal Endothelial Cell Loss - diagnosis
Corneal Endothelial Cell Loss - etiology
coronavirus disease 2019
COVID-19
endothelium
Endothelium, Corneal - pathology
Endothelium, Corneal - virology
Eye Infections, Viral - diagnosis
Eye Infections, Viral - virology
Female
Humans
Male
Microscopy - methods
Middle Aged
optical biometry
Prospective Studies
SARS-CoV-2
specular microscopy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:This study aimed to investigate the effects of severe COVID-19 infection on the corneal endothelium via in vivo specular microscopy. This was an observational, prospective, and controlled study including 56 eyes of 56 severe COVID-19 patients, compared to after-recovery and 56 eyes of 56 age- and gender-matched healthy controls. Endothelial cell density was lower in the active disease period compared to healthy controls (p = .001) and decreased even more after recovery (p 
ISSN:0927-3948
1744-5078
1744-5078
DOI:10.1080/09273948.2023.2219312