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Community outreach with weekly delivery of anti-retroviral drugs compared to cognitive-behavioural health care team-based approach to improve adherence among indigent women newly starting HAART
Sustained virological suppression requires adherence to >95% of doses of therapy. Overall there is paucity of data on adherence interventions among women and post-intervention outcomes. In this pilot study, we evaluated a novel strategy of weekly delivery of medications (Directly Delivered Therap...
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| Published in: | AIDS care 2006-05, Vol.18 (4), p.332-338 |
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| Main Authors: | , , , , , |
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| cites | cdi_FETCH-LOGICAL-c550t-ea646c8fe7e6453ef458f60ed1b3a6144f81c8592491bfb61d39175dbf47e71f3 |
| container_end_page | 338 |
| container_issue | 4 |
| container_start_page | 332 |
| container_title | AIDS care |
| container_volume | 18 |
| creator | Visnegarwala, F. Rodriguez-Barradass, M. C. Graviss, E. A. Caprio, M. Nykyforchyn, M. Laufman, L. |
| description | Sustained virological suppression requires adherence to >95% of doses of therapy. Overall there is paucity of data on adherence interventions among women and post-intervention outcomes. In this pilot study, we evaluated a novel strategy of weekly delivery of medications (Directly Delivered Therapy: DDT) for six months using an outreach worker (ORW), among ARV naïve indigent women starting HAART and compared the 'during intervention' and 'post-intervention' outcomes to the health care team (a nurse educator, a case worker, a pharmacist and social worker/drug addictions counsellor) based approach termed Adherence Coordination Services (ACS) and the Standard of Care (SoC) historical referent group. The baseline characteristics of the three groups were comparable. The proportion of women who achieved sustained virologic suppression in 4-8 month period for DDT; ACS and SoC groups were 86% (18/21); 54% (6/11); and 36% (8/22) (P |
| doi_str_mv | 10.1080/09540120500162155 |
| format | article |
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C. ; Graviss, E. A. ; Caprio, M. ; Nykyforchyn, M. ; Laufman, L.</creator><creatorcontrib>Visnegarwala, F. ; Rodriguez-Barradass, M. C. ; Graviss, E. A. ; Caprio, M. ; Nykyforchyn, M. ; Laufman, L.</creatorcontrib><description>Sustained virological suppression requires adherence to >95% of doses of therapy. Overall there is paucity of data on adherence interventions among women and post-intervention outcomes. In this pilot study, we evaluated a novel strategy of weekly delivery of medications (Directly Delivered Therapy: DDT) for six months using an outreach worker (ORW), among ARV naïve indigent women starting HAART and compared the 'during intervention' and 'post-intervention' outcomes to the health care team (a nurse educator, a case worker, a pharmacist and social worker/drug addictions counsellor) based approach termed Adherence Coordination Services (ACS) and the Standard of Care (SoC) historical referent group. The baseline characteristics of the three groups were comparable. The proportion of women who achieved sustained virologic suppression in 4-8 month period for DDT; ACS and SoC groups were 86% (18/21); 54% (6/11); and 36% (8/22) (P<0.004); and in the 10-14 month period were 80% (12/15); 54% (6/11) and 45%(10/22) (P=0.036 for DDT vs. SoC). Retention rate in the DDT was 87%, and 92% of 307 ORW visits were kept, and post-intervention satisfaction was high. 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May 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c550t-ea646c8fe7e6453ef458f60ed1b3a6144f81c8592491bfb61d39175dbf47e71f3</citedby><cites>FETCH-LOGICAL-c550t-ea646c8fe7e6453ef458f60ed1b3a6144f81c8592491bfb61d39175dbf47e71f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925,30999,31000,33223,33224</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17824753$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16809110$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Visnegarwala, F.</creatorcontrib><creatorcontrib>Rodriguez-Barradass, M. C.</creatorcontrib><creatorcontrib>Graviss, E. A.</creatorcontrib><creatorcontrib>Caprio, M.</creatorcontrib><creatorcontrib>Nykyforchyn, M.</creatorcontrib><creatorcontrib>Laufman, L.</creatorcontrib><title>Community outreach with weekly delivery of anti-retroviral drugs compared to cognitive-behavioural health care team-based approach to improve adherence among indigent women newly starting HAART</title><title>AIDS care</title><addtitle>AIDS Care</addtitle><description>Sustained virological suppression requires adherence to >95% of doses of therapy. Overall there is paucity of data on adherence interventions among women and post-intervention outcomes. In this pilot study, we evaluated a novel strategy of weekly delivery of medications (Directly Delivered Therapy: DDT) for six months using an outreach worker (ORW), among ARV naïve indigent women starting HAART and compared the 'during intervention' and 'post-intervention' outcomes to the health care team (a nurse educator, a case worker, a pharmacist and social worker/drug addictions counsellor) based approach termed Adherence Coordination Services (ACS) and the Standard of Care (SoC) historical referent group. The baseline characteristics of the three groups were comparable. The proportion of women who achieved sustained virologic suppression in 4-8 month period for DDT; ACS and SoC groups were 86% (18/21); 54% (6/11); and 36% (8/22) (P<0.004); and in the 10-14 month period were 80% (12/15); 54% (6/11) and 45%(10/22) (P=0.036 for DDT vs. SoC). Retention rate in the DDT was 87%, and 92% of 307 ORW visits were kept, and post-intervention satisfaction was high. Short-term weekly delivery of medications using a community based liaison is a feasible, acceptable and a cost-effective strategy for improving both short-term and perhaps long-term adherence among women initiating their first HAART regimen.</description><subject>Acquired immune deficiency syndrome</subject><subject>Adherence</subject><subject>Adult</subject><subject>AIDS</subject><subject>AIDS/HIV</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiretroviral drugs</subject><subject>Antiretroviral Therapy</subject><subject>Antiretroviral Therapy, Highly Active</subject><subject>Antiviral agents</subject><subject>Biological and medical sciences</subject><subject>Clinical outcomes</subject><subject>Cognitive Behaviour Therapy</subject><subject>Cognitive Therapy - methods</subject><subject>Community Health Services</subject><subject>Community treatment. Ambulatory treatment. Home care</subject><subject>Compliance</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Health care</subject><subject>Health services</subject><subject>HIV</subject><subject>HIV Infections - therapy</subject><subject>Human immunodeficiency virus</subject><subject>Humans</subject><subject>Interventions</subject><subject>Low income groups</subject><subject>Medical sciences</subject><subject>Medical treatment</subject><subject>Outreach programmes</subject><subject>Patient Acceptance of Health Care - statistics & numerical data</subject><subject>Patient Compliance</subject><subject>Pharmacology. Drug treatments</subject><subject>Pilot Projects</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Sexual health</subject><subject>Texas</subject><subject>Treatment Outcome</subject><subject>Treatments</subject><subject>Women</subject><issn>0954-0121</issn><issn>1360-0451</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>7QJ</sourceid><sourceid>8BJ</sourceid><recordid>eNqNktGK1DAUhoso7rj6AN5IENa76jlt06bgzTCoKywIsl6XtD2ZydomY5LOOI_nm5kyIwsuON4kB873_-cnOUnyEuEtgoB3UPMCMAMOgGWGnD9KFpiXkELB8XGymPtpBPAieeb9HQBkUMLT5AJLATUiLJJfKzuOk9HhwOwUHMluw_Y6xIPo-3BgPQ16Ry52FZMm6NRRcHannRxY76a1Z50dt9JRz4KN9TpaRUHa0kbutJ1mbkNyiI5dpFggOaat9JGX262z87wo1GOsd8RkvyFHpovVaM2aadPrNZnA9nYkwwztYyYfpAs6dq-Xy6-3z5MnSg6eXpzuy-Tbxw-3q-v05sunz6vlTdpxDiElWRZlJxRVVBY8J1VwoUqgHttcllgUSmAneJ0VNbaqLbHPa6x436qiogpVfpm8OfrGpD8m8qEZte9oGKQhO_mmFFwIweEsyCvgMYI4C-Yx8X-BWNdCZDiPfv0XeBe_wMRnaTJAHhGc3fAIdc5670g1W6dH6Q4NQjPvVfNgr6Lm1cl4akfq7xWnRYrA1QmQvpODctJ02t9zlciKiueRe3_ktFHWjXJv3dA3QR4G6_6I8n_lqM7KH6ia8DPkvwFrCf2H</recordid><startdate>20060501</startdate><enddate>20060501</enddate><creator>Visnegarwala, F.</creator><creator>Rodriguez-Barradass, M. 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Short-term weekly delivery of medications using a community based liaison is a feasible, acceptable and a cost-effective strategy for improving both short-term and perhaps long-term adherence among women initiating their first HAART regimen.</abstract><cop>Abingdon</cop><pub>Taylor & Francis Group</pub><pmid>16809110</pmid><doi>10.1080/09540120500162155</doi><tpages>7</tpages></addata></record> |
| fulltext | fulltext |
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| ispartof | AIDS care, 2006-05, Vol.18 (4), p.332-338 |
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| language | eng |
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| source | Applied Social Sciences Index & Abstracts (ASSIA); International Bibliography of the Social Sciences (IBSS); Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Acquired immune deficiency syndrome Adherence Adult AIDS AIDS/HIV Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral drugs Antiretroviral Therapy Antiretroviral Therapy, Highly Active Antiviral agents Biological and medical sciences Clinical outcomes Cognitive Behaviour Therapy Cognitive Therapy - methods Community Health Services Community treatment. Ambulatory treatment. Home care Compliance Drug therapy Female Health care Health services HIV HIV Infections - therapy Human immunodeficiency virus Humans Interventions Low income groups Medical sciences Medical treatment Outreach programmes Patient Acceptance of Health Care - statistics & numerical data Patient Compliance Pharmacology. Drug treatments Pilot Projects Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Sexual health Texas Treatment Outcome Treatments Women |
| title | Community outreach with weekly delivery of anti-retroviral drugs compared to cognitive-behavioural health care team-based approach to improve adherence among indigent women newly starting HAART |
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