Small, qualitative changes in fatty acid intake decrease plasma low-density lipoprotein-cholesterol levels in mildly hypercholesterolemic outpatients on their usual high-fat diets

Objective The diet is the first step in managing hypercholesterolemia. The objective of the present study is to assess whether moderate changes in dietary fatty acids improve plasma lipid parameters in mildly hypercholesterolemic outpatients. Methods Using a randomized double-blind study, 121 outpat...

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Bibliographic Details
Published in:International journal of food sciences and nutrition 2009-01, Vol.60 (s7), p.151-163
Main Authors: Lecerf, Jean-Michel, Luc, Gérald, Marécaux, Nadine, Bal, Sylvie, Bonte, Jean-Paul, Lacroix, Brigitte, Cayzeele, Amélie
Format: Article
Language:English
Subjects:
Adult
Aged
Atherosclerosis - prevention & control
Butter - analysis
cardiovascular risk
Cholesterol, LDL - blood
Comparative analysis
Correlation analysis
Diet
Diet Records
Diet, Atherogenic
Dietary Fats, Unsaturated - administration & dosage
Double-Blind Method
Early Diagnosis
Fatty acids
Female
Food science
Health Promotion
Humans
hypercholesterolemia
Hypercholesterolemia - blood
Hypercholesterolemia - diet therapy
Lipids
Low density lipoprotein
Low-density lipoprotein cholesterol
Male
margarine
Margarine - analysis
Middle Aged
Outpatients
Patient Compliance
Plasma
Risk Factors
Statistics as Topic
Citations: Items that this one cites
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Summary:Objective The diet is the first step in managing hypercholesterolemia. The objective of the present study is to assess whether moderate changes in dietary fatty acids improve plasma lipid parameters in mildly hypercholesterolemic outpatients. Methods Using a randomized double-blind study, 121 outpatients within two groups received an isocaloric amount of unsaturated margarine or butter. Clinical and anthropometric measurements and a 3-day food record were made. Chi-square and Fisher's tests were used to compare qualitative variables and the general linear procedure was used to compare the groups. Additional analyses were performed after adjustment. Results There was a significant difference (P
ISSN:0963-7486
1465-3478
DOI:10.1080/09637480902758727