Vitamin D immunoassay systems: a comparison

[...]there has been rising clinical demand for the assessment of vitamin D status.5,6 The total 25(OH)D level (the sum of D2 and D3) is the best indicator of vitamin D body stores.7,8 Currently, there is great variation and a lack of standardisation in the methods used for vitamin D measurement, res...

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Bibliographic Details
Published in:British journal of biomedical science 2014-01, Vol.71 (3), p.127-130
Main Authors: Dafterdar, R., Al-Fayoumi, M., Saadeddin, S., Khan, R., Alothaim, A., Hasanato, R., Al-Shangiti, A., Fakhoury, H., Tamimi, W.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Architects
Automation
Bias
Bone density
Child
Child, Preschool
Chromatography
Chromatography, High Pressure Liquid
Confidence intervals
Female
Humans
Immunoassay - methods
Infant
Laboratories
Male
Methods
Middle Aged
Older people
Regression Analysis
Shipments
Studies
Vitamin D
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - diagnosis
Vitamin deficiency
Young Adult
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Summary:[...]there has been rising clinical demand for the assessment of vitamin D status.5,6 The total 25(OH)D level (the sum of D2 and D3) is the best indicator of vitamin D body stores.7,8 Currently, there is great variation and a lack of standardisation in the methods used for vitamin D measurement, resulting in considerable uncertainty. [...]a simple and high-throughput method for reliably measuring vitamin D level has become an absolute requirement for clinical laboratories.9 In response to the need for vitamin D testing, different automated assays for measuring the 25(OH)D level have been developed and released by different companies.
ISSN:0967-4845
2474-0896
DOI:10.1080/09674845.2014.11978289