Preparation and Characterization of Vanillin Cross-Linked Chitosan Microspheres of Pterostilbene

A vanillin cross-linked chitosan microsphere delivery system was established for stabilization and controlled release of pterostilbene. The prepared microspheres were characterized by SEM images, FT-IR spectra, thermogravimetry, and X-ray diffraction. FT-IR spectra results indicated that chitosan wa...

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Bibliographic Details
Published in:International journal of polymer analysis & characterization 2014-01, Vol.19 (1), p.83-93
Main Authors: Zhang, Yue, Shi, Xianxian, Yu, Yifeng, Zhao, Shuchun, Song, Haiwen, Chen, Aibing, Shang, Zhenhua
Format: Article
Language:English
Subjects:
Characterization
Chemical compounds
Chitosan
Chitosan microspheres
Controlled release
Crosslinking
Delivery systems
Microspheres
Polyphenols
Pterostilbene
Spectra
Spectrum analysis
Stability
Stabilization
Vanillin
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Summary:A vanillin cross-linked chitosan microsphere delivery system was established for stabilization and controlled release of pterostilbene. The prepared microspheres were characterized by SEM images, FT-IR spectra, thermogravimetry, and X-ray diffraction. FT-IR spectra results indicated that chitosan was cross-linked by vanillin successfully. Thermal analysis showed that pterostilbene had been totally incorporated into the microspheres and the encapsulation of pterostilbene decreases the rate of degradation and increases the stability. XRD analysis was conducted to confirm the results of DSC analysis. The release rate of pterostilbene from microspheres in pH 3.6 buffer solution could be up to 58.1 % within 48 h.
ISSN:1023-666X
1563-5341
DOI:10.1080/1023666X.2014.864488