The impact of calcification patterns in transcatheter aortic valve performance: a fluid-structure interaction analysis

Transcatheter aortic valve replacement (TAVR) strongly depends on the calcification patterns, which may lead to a malapposition of the stented valve and complication onsets in terms of structure kinematics and paravalvular leakage (PVL). From one anatomical-resembling model of the aortic root, six c...

Full description

Saved in:
Bibliographic Details
Published in:Computer methods in biomechanics and biomedical engineering 2021-03, Vol.24 (4), p.375-383
Main Authors: Luraghi, Giulia, Matas, Jose Felix Rodriguez, Beretta, Marta, Chiozzi, Nicole, Iannetti, Laura, Migliavacca, Francesco
Format: Article
Language:English
Subjects:
Aorta
Aortic valve
Calcification
Calcification (ectopic)
Configurations
Deposits
finite element analysis
Fluid-structure interaction
Heart valves
Kinematics
paravalvular leakage
Transcatheter aortic valve
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Transcatheter aortic valve replacement (TAVR) strongly depends on the calcification patterns, which may lead to a malapposition of the stented valve and complication onsets in terms of structure kinematics and paravalvular leakage (PVL). From one anatomical-resembling model of the aortic root, six configurations with different calcific deposits were built. TAVR fluid-structure interaction simulations predicted different outcomes for the different calcifications patterns in terms of the final valve configuration in the implantation site and the PVL estimations. In particular models with deposits along the cups coaptation resulted in mild PVL, while those with deposits along the attachment line in moderate PVL.
ISSN:1025-5842
1476-8259
DOI:10.1080/10255842.2020.1817409