The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection

Epigallocatechin gallate is the most abundant composition of the tea catechins and is thought to be responsible for the majority of biological activity of green tea extracts such as antioxidant, anti-inflammatory, and antiapoptotic effects. Meanwhile, EGCG has been shown to be some of the neuroprote...

Full description

Saved in:
Bibliographic Details
Published in:Nutritional neuroscience 2020-04, Vol.23 (4), p.281-294
Main Authors: Khalatbary, Ali Reza, Khademi, Emad
Format: Article
Language:English
Subjects:
Animals
Apoptosis - drug effects
Brain - metabolism
Brain Injuries - metabolism
Brain Injuries - prevention & control
Catechin - administration & dosage
Catechin - analogs & derivatives
Catechin - metabolism
Clinical Trials as Topic
Epigallocatechin gallate
Humans
in vitro
in vivo
Neurodegenerative Diseases - metabolism
Neurodegenerative Diseases - prevention & control
Neurons - metabolism
Neuroprotection
Neuroprotective Agents - administration & dosage
Plant Extracts - administration & dosage
Spinal Cord Injuries - metabolism
Spinal Cord Injuries - prevention & control
Tea
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Epigallocatechin gallate is the most abundant composition of the tea catechins and is thought to be responsible for the majority of biological activity of green tea extracts such as antioxidant, anti-inflammatory, and antiapoptotic effects. Meanwhile, EGCG has been shown to be some of the neuroprotective effects against neural injuries and neurodegenerative diseases. This paper summarizes current knowledge on neuroprotective effects of EGCG and their molecular mechanisms responsible for the neuroprotection in various models of neurodegenerative and neural injury.
ISSN:1028-415X
1476-8305
DOI:10.1080/1028415X.2018.1500124