C 21 steroidal glycosides from Cynanchum taihangense

Two new C steroidal glycosides, cynataihosides E (1) and F (2), together with a known one, sublanceoside H (3), were isolated from Cynanchum taihangense. The aglycone of cynataihoside F (2) was also a new compound. Their structures were elucidated on the basis of NMR spectroscopic data, HR-ESI-MS an...

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Bibliographic Details
Published in:Journal of asian natural products research 2018-03, Vol.20 (3), p.1-269
Main Authors: Wang, Yu-Bo, Su, Shan-Shan, Chen, Shao-Fei, Tang, Ming-Xu, Chen, Gang, Zhao, Dan, Sang, Xia-Nan, Si, Ying-Ying, Wang, Hai-Feng, Pei, Yue-Hu
Format: Article
Language:English
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Summary:Two new C steroidal glycosides, cynataihosides E (1) and F (2), together with a known one, sublanceoside H (3), were isolated from Cynanchum taihangense. The aglycone of cynataihoside F (2) was also a new compound. Their structures were elucidated on the basis of NMR spectroscopic data, HR-ESI-MS analysis, and chemical evidence. Their cytotoxic activities against three human tumor cell lines (HL-60, THP1, and Caco2) were reported.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2017.1329302