Asperpenes D and E from the fungus Aspergillus sp. SCS-KFD66 isolated from a bivalve mollusk, Sanguinolaria chinensis

Two new compounds named asperpenes D (1) and E (2) were isolated from the marine-derived fungus Aspergillus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound 2 represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2,5-dihydrofuran-3...

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Bibliographic Details
Published in:Journal of asian natural products research 2021-02, Vol.23 (2), p.117-122
Main Authors: An, Chang-Liang, Kong, Fan-Dong, Li, Yan, Ma, Qing-Yun, Xie, Qing-Yi, Yuan, Jing-Zhe, Zhou, Li-Man, Dai, Hao-Fu, Yu, Zhi-Fang, Zhao, You-Xing
Format: Article
Language:English
Subjects:
alpha-Glucosidases
Animals
Aspergillus
Aspergillus sp
Biological Products
Bivalvia
Carboxylic acids
Fungi
Glucosidase
Marine-derived fungus
Molecular Structure
Mollusks
Natural products
Scavenging
secondary metabolites
Shellfish
α-Glucosidase
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Summary:Two new compounds named asperpenes D (1) and E (2) were isolated from the marine-derived fungus Aspergillus sp. SCS-KFD66. Their structures were determined on the basis of spectroscopic methods. Compound 2 represents the first natural product bearing a 2-substituted-5-oxo-4-phenyl-2,5-dihydrofuran-3-carboxylic acid skeleton. All the compounds were tested for enzyme inhibitory activity against AChE and α-glucosidase and DPPH radical scavenging activity, respectively.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2019.1709450