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Three new sesquiterpenes from Ixeris sonchifolia

Two new guaiacene-type sesquiterpenes 13α-dihydroixerin acid, ixerin acid and one new secoguaiacene-type sesquiterpene secoixerin Z, along with four known compounds, were separated from ethanol extract of Ixeris sonchifolia. The structures were determined based on the detailed spectroscopic and phys...

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Bibliographic Details
Published in:Journal of asian natural products research 2023-06, Vol.25 (6), p.557-563
Main Authors: Tang, Meng, Tang, Shu-Han, Huang, Jin-Yue, Hattori, Masao, Zhang, Ning, Yang, Bo, Wu, Xiu-Hong, Zhang, Hai-Long, Wang, Zhi-Gang
Format: Article
Language:English
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Summary:Two new guaiacene-type sesquiterpenes 13α-dihydroixerin acid, ixerin acid and one new secoguaiacene-type sesquiterpene secoixerin Z, along with four known compounds, were separated from ethanol extract of Ixeris sonchifolia. The structures were determined based on the detailed spectroscopic and physicochemical methods. The cytotoxic activity of the isolates was tested against A549 cells. Among them, compound 3 exhibited potent cytotoxicity against A549 cells with the IC 50 of 5.6 ± 0.9 µM.
ISSN:1028-6020
1477-2213
DOI:10.1080/10286020.2022.2126358