Polysaccharides in Lentinus edodes: Isolation, Structure, Immunomodulating Activity and Future Prospective

Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes . In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extr...

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Bibliographic Details
Published in:Critical reviews in food science and nutrition 2014-01, Vol.54 (4), p.474-487
Main Authors: Xu, Xiaofei, Yan, Huidan, Tang, Jian, Chen, Jian, Zhang, Xuewu
Format: Article
Language:English
Subjects:
adaptive immunity
Antineoplastic Agents - chemistry
Antineoplastic Agents - pharmacology
antitumor
Biological and medical sciences
Carbohydrates
chemical structure
Feeding. Feeding behavior
food science
Fundamental and applied biological sciences. Psychology
Immunology
immunomodulation
Immunomodulation - drug effects
lentinan
Lentinula edodes
Lentinus edodes
Mushrooms
Nutrition research
nutrition science
polysaccharide
polysaccharides
Polysaccharides - chemistry
purification methods
Shiitake Mushrooms - chemistry
Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Summary:Lentinus edodes has been valued as edible and medical resources. Polysaccharides have been known to be the most potent antitumor and immunomodulating substance in Lentinus edodes . In this review, we summarize the current knowledge of the polysaccharides isolated from Lentinus edodes, including extraction and purification methods, chemical structure and chain conformation, the effects on innate and adaptive immunity and their mechanism, relationship between structure and function, and the future prospects.
ISSN:1549-7852
1040-8398
1549-7852
DOI:10.1080/10408398.2011.587616