Selection signatures of Qinchuan cattle based on whole-genome sequences

Qinchuan cattle has gradually improved in body shape and growth rate in the long-term breeding process from the draft cattle to beef cattle. As the head of the five local yellow cattle in China, the Qinchuan cattle has been designated as a specialized beef cattle breed. We investigated the selection...

Full description

Saved in:
Bibliographic Details
Published in:Animal biotechnology 2023-11, Vol.34 (4), p.1483-1491
Main Authors: Wang, Sihu, Raza, Sayed Haidar Abbas, Zhang, Ke, Mei, Chugang, Alamoudi, Muna O., Aloufi, Bandar H., Alshammari, Ahmed Mohajja, Zan, Linsen
Format: Article
Language:English
Subjects:
Animal breeding
Animal production
Annotations
Beef
Beef cattle
Body size
Breeding
Cattle
Gene sequencing
Genes
genome selection
Genomes
molecular genetic breeding
Protein interaction
Proteins
Qinchuan cattle
selective signature
Signatures
USH2A protein
Whole genome sequencing
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Qinchuan cattle has gradually improved in body shape and growth rate in the long-term breeding process from the draft cattle to beef cattle. As the head of the five local yellow cattle in China, the Qinchuan cattle has been designated as a specialized beef cattle breed. We investigated the selection signatures using whole genome sequencing data in Qinchuan cattle. Based on Fst, we detected hundreds of candidate genes under selection across Qinchuan, Red Angus, and Japanese Black cattle. Through protein-protein interaction analysis and functional annotation of candidate genes, the results revealed that KMT2E, LTBP1 and NIPBL were related to brain size, body characteristics, and limb development, respectively, suggesting that these potential genes may affect the growth and development traits in Qinchuan cattle. ARIH2, DACT1 and DNM2, et al. are related to meat quality. Meanwhile, TBXA2R can be used as a gene associated with reproductive function, and USH2A affect coat color. This provided a glimpse into the formation of breeds and molecular genetic breeding. Our findings will promote genome-assisted breeding to improve animal production and health.
ISSN:1049-5398
1532-2378
DOI:10.1080/10495398.2022.2033252