Dietary exposure of Finnish children to heavy metal mixture - a cumulative assessment

A preliminary assessment of the cumulative exposure to heavy metals among Finnish preschool children is reported. Cadmium, lead, arsenic,and mercury affect many of the same organs in the human body. The effects are mostly caused by oxidative stress or disruption of enzyme function. The cumulative ef...

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Bibliographic Details
Published in:Human and ecological risk assessment 2017-07, Vol.23 (5), p.1234-1248
Main Authors: Suomi, Johanna, Tuominen, Pirkko, Savela, Kirsti
Format: Article
Language:English
Subjects:
Arsenic
Cadmium
Central nervous system
Children
cumulative exposure assessment
Diet
dietary exposure
Disruption
Exposure
Heavy metals
Kidneys
Lead
Mercury
Mercury (metal)
Metals
Nervous system
Neurotoxicity
Organs
Oxidative stress
Population studies
Preschool children
Stress concentration
Toxicity
Water pollution effects
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Summary:A preliminary assessment of the cumulative exposure to heavy metals among Finnish preschool children is reported. Cadmium, lead, arsenic,and mercury affect many of the same organs in the human body. The effects are mostly caused by oxidative stress or disruption of enzyme function. The cumulative effects of the heavy metals on the central nervous system and on the kidneys are determined based on national concentration and consumption data, and comparison of the relative toxicity of the heavy metals is based on dose-response values found in the literature. The cumulative effects were assumed to be additive. The main contributors to kidney toxicity among the studied population groups were cadmium and lead, while lead was the main contributor to neurotoxic effects.
ISSN:1080-7039
1549-7860
DOI:10.1080/10807039.2017.1314760