Antibacterial and antibiofilm activity of extracts from sponge-associated bacterial endophytes

Sponges forms association with many bacteria that serve as sources of new bioactive compounds. The compounds are produced in response to environmental and nutritional conditions of the environment that enable them to protect their host from colonization. In this study, three sponge bacterial endophy...

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Bibliographic Details
Published in:Preparative biochemistry & biotechnology 2023-10, Vol.53 (9), p.1143-1153
Main Authors: Abdulrahman, Idris, Jamal, Mamdoh Taha, Pugazhendi, Arulazhagan, Dhavamani, Jeyakumar, Al-shaeri, Majed, Al-Maaqar, Saleh, Satheesh, Sathianeson
Format: Article
Language:English
Subjects:
Antibacterial activity
antibiofilm
Antifouling substances
Bacteria
Bioactive compounds
Biological activity
Chemical composition
Colonization
culture medium
Endophytes
extraction of metabolite
Fermentation
Fouling
Gas chromatography
Mass spectrometry
Mass spectroscopy
Metabolites
optimization
Secondary metabolites
Solvent extraction
sponge
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Summary:Sponges forms association with many bacteria that serve as sources of new bioactive compounds. The compounds are produced in response to environmental and nutritional conditions of the environment that enable them to protect their host from colonization. In this study, three sponge bacterial endophytes were isolated, identified, and subjected to solvent extraction processes. The identified bacteria are Bacillus amyloquifaciens, Bacillus paramycoides, and Enterobacter sp. The bacteria were cultured in two different fermentation media with varying nutritional composition for the extraction process. The extracts were evaluated for antibacterial and antibiofilm activity against microfouling bacteria and the chemical composition of each extract was analyzed via gas chromatography-mass spectrometry (GC-MS). The extract from the endophytes shows varying antibacterial and antibiofilm activity against the tested strains. Several compounds were detected from the extracts including some with known antibacterial/antibiofilm activity. The results showed variations in activity and secondary metabolite production between the extracts obtained under different nutritional composition of the media. In conclusion, this study indicated the role of nutrient composition in the activity and secondary metabolites production by bacteria associated with sponge Also, this study confirmed the role of sponge bacterial endophytes as producers of bioactive compounds with potential application as antifouling (AF) agents.
ISSN:1082-6068
1532-2297
DOI:10.1080/10826068.2023.2175366