SEPARATION OF CLUSIANONE FROM CLUSIA FLUMINENSIS PLANCH. AND TRIANA (CLUSIACEAE) BY HIGH SPEED COUNTER-CURRENT CHROMATOGRAPHY (HSCCC)

The floral resins of the genus Clusia L. (Clusiaceae Lindl.) mainly consist of polyisoprenylated benzophenones, a class of substances which is noteworthy due to its broad spectrum of biological activities. This paper describes the isolation of clusianone from the male flowers of Clusia fluminensis P...

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Bibliographic Details
Published in:Journal of liquid chromatography & related technologies 2012-10, Vol.35 (16), p.2313-2321
Main Authors: Anholeti da Silva, Maria Carolina, Heringer, Alan Patrick, Figueiredo, Maria Raquel, de Paiva, Selma Ribeiro
Format: Article
Language:English
Subjects:
benzophenones
Biological and medical sciences
Clusia
Clusia fluminensis
Clusiaceae
clusianone
General pharmacology
HSCCC
Indexing in process
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
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Summary:The floral resins of the genus Clusia L. (Clusiaceae Lindl.) mainly consist of polyisoprenylated benzophenones, a class of substances which is noteworthy due to its broad spectrum of biological activities. This paper describes the isolation of clusianone from the male flowers of Clusia fluminensis Planch. & Triana, a native species from the Brazilian coast, using, for the first time, high-speed counter-current chromatography with a nonaqueous solvent system composed of n-hexane-acetonitrile-methanol (2:1.25:0.5, v/v/v) in 2 hr, with purity higher than 90%.
ISSN:1082-6076
1520-572X
DOI:10.1080/10826076.2011.631261