Activités antivirale et antioxydante in vitro d'huiles essentielles de Thymus capitatus (L.) Hoffmans. & Link de Tunisie

Three essential oil samples of Thymus capitatus (L.) Hoffmans. & Link were tested for cytotoxicity by MTT assay in Vero cells and antiviral activity against type 1 Herpes simplex virus (HSV1), Echovirus 11 (ECV11) and Adenovirus (ADV) using cytopathic effect (CPE) reduction essay. In order to de...

Full description

Saved in:
Bibliographic Details
Published in:Acta botanica gallica 2010-01, Vol.157 (3), p.433-444
Main Authors: Salah-Fatnassi, Karima Bel Hadj, Slim-Bannour, Amira, Harzallah-Skhiri, Fathia, Mahjoub, Mohamed Ali, Mighri, Zine, Chaumont, Jean-Pierre, Aouni, Mahjoub
Format: Article
Language:English
Subjects:
ABTS
activité antioxydante
activité antivirale
antioxidant activity
antiviral activity
cytotoxicity
cytotoxicité
DPPH
essential oil
huile essentielle
Thymus capitatus
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Three essential oil samples of Thymus capitatus (L.) Hoffmans. & Link were tested for cytotoxicity by MTT assay in Vero cells and antiviral activity against type 1 Herpes simplex virus (HSV1), Echovirus 11 (ECV11) and Adenovirus (ADV) using cytopathic effect (CPE) reduction essay. In order to determine the mode of antiviral action of the essential oil, thyme was added at different times to the cells or viruses during infection. Both HSV1 and ECV11 were significantly inhibited when virus were pretreated with the essential oil prior to adsorption, while ADV was affected after penetration into the host cell. In vitro antioxidant properties of the essential oils, obtained by DPPH and ABTS assays, were interesting compared to the synthetic antioxidant Trolox.
ISSN:1253-8078
2166-3408
DOI:10.1080/12538078.2010.10516220